Leadiant Biosciences, S.p.A is a Rome-based global holding company, with subsidiaries in the US (Leadiant Biosciences, Inc.) and Europe (Leadiant Biosciences, Ltd). For region or country-specific product information, use the dropdown below.

Brand name (active ingredient) Disease Area Stage of commercialization Company
(Chenodeoxycholic acid) Cerebrotendinous Xanthomatosis Under registration with EMA Leadiant Biosciences Ltd.
Natulan (procarbazine) Hodgkin lymphoma and brain cancers Registered Leadiant Biosciences Ltd.
elapegademase adenosine deaminase severe combined immunodeficiency (ADA – SCID) Phase III Leadiant Biosciences, Inc.
chenodiol cerebrotendinous xanthomatosis (CTX) NDA submitted Leadiant Biosciences, Inc.
Matulane® (procarbazine hydrochloride) oligodendrogliomas, oligoastrocytomas, and astrocytomas sNDA preparation Leadiant Biosciences, Inc.
Abelcet® (amphotericin B lipid complex injection) Invasive fungal infections Marketed Leadiant Biosciences, Inc.
Adagen® (pegademase bovine) adenosine deaminase severe combined immunodeficiency (ADA – SCID) Marketed Leadiant Biosciences, Inc.
Carnitor® (levocarnitine) Tablets, Oral Solution, Sugar-Free Oral Solution, and Injection carnitine deficiency Marketed Leadiant Biosciences, Inc.
Cystaran® (cysteamine ophthalmic solution) 0.44% cystinosis Marketed Leadiant Biosciences, Inc.
DepoCyt® (cytarabine liposome injection) lymphomatous meningitis Marketed Leadiant Biosciences, Inc.
Matulane® (procarbazine hydrochloride) Capsules Hodgkin’s disease Marketed Leadiant Biosciences, Inc.

Marketed products

Brand name (active ingredient)  Disease Area Region/Country of approval Affiliated Company
Chenodeoxycholic acid Leadiant (chenodeoxycholic acid) Metabolic Europe Leadiant Biosciences, Ltd.
Natulan (procarbazine hydrochoride) Oncology Europe Leadiant Biosciences, Ltd.
Abelcet® (amphotericin B lipid complex injection) Infectious disease  US, Canada Leadiant Biosciences, Inc.
Adagen® (pegademase bovine) Immunology US Leadiant Biosciences, Inc.
Carnitor® (levocarnitine) Tablets, Oral Solution, Sugar-Free Oral Solution, and Injection Metabolic disease/Nephrology  US Leadiant Biosciences, Inc.
Carnitor® (levocarnitine) Tablets, Oral Solution, and Injection Metabolic disease/Nephrology Canada Leadiant Biosciences, Inc.
Cystaran® (cysteamine ophthalmic solution) 0.44% Metabolic disease / ophthalmology  US Leadiant Biosciences, Inc.
DepoCyt® (cytarabine liposome injection)  Oncology  US Leadiant Biosciences, Inc.
Matulane® (procarbazine hydrochloride)  Oncology  US, Canada Leadiant Biosciences, Inc.

Updated June 2017

Important Note

For patients: if you wish to report an adverse event related to one of our products, please contact your healthcare provider. In addition, you can contact us on safety@leadiantbiosciences.com.

For healthcare professionals: if you wish to report an adverse event related to one of our products, please follow the current regulatory procedure in force in your country or contact us at safety@leadiantbiosciences.com.

For patients or healthcare professionals in the United States and Canada: if you wish to report an adverse event related to one of our products, please contact us at leadiant@tmacmail.com.